Peyton Hillis injured again during Browns practice on Friday

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Peyton Hillis has re-injured the left hamstring that has kept him out of the Cleveland Browns’ last two games.

In just his second day back in practice since last week, the star running back pulled up after a running play on Friday, throwing the ball and his helmet in frustration before being taken back to the team’s facility by a trainer.

The development appears to put an end the Browns’ hopes that Hillis would be ready to play Sunday at Houston. Coach Pat Shurmur is expected to have an update after Friday’s practice.

Hillis rushed for 1,177 yards and 11 touchdowns, both career highs, in his first year with the Browns in 2010. But the fourth-year pro has not had a successful follow-up season. He missed an additional game because of strep throat and has sniffed 100 yards only once this year (94 yards against the woeful Colts in Week 2).

He also has been involved in a contract disagreement with the team and this week was criticized for missing a Halloween event for the Boys & Girls Club that he was supposed to attend. He later apologized for not attending the event, saying there had been a miscommunication between him and his management.

Friday’s development might be the most frustrating of all for Hillis, who made it through practice Thursday with no problem and had expressed optimism for being able to play Sunday.

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-- Chuck Schilken

The Associated Press contributed to this report.