Guitarist Sambora is checking into rehab to treat his exhaustion and deal with sobriety issues, RadarOnline reported.
In a statement on the rock band's website, Bon Jovi said it will proceed with its upcoming tour without Sambora.
"Our support for Richie is absolute," the statement said. "He is, and will remain, a member of Bon Jovi. Although he will be absent from upcoming shows for the time being, we very much look forward to his healthy return. In the meantime, we will keep our commitment to our fans and continue our tour."
The group kicks off its North America tour Saturday in New Orleans before heading to Europe in June.
This isn't Sambora's first stint in rehab.
The rocker, who spoke about his addiction to painkillers in the Bon Jovi documentary "When We Were Beautiful," checked into rehab twice in 2007 -- the year his divorce from Heather Locklear was finalized, his father died from lung cancer, and he split with girlfriend Denise Richards.
Sambora also pleaded no contest to DUI in 2008.
"Richie has had a busy year," a source told Radar. "I think this was a culmination of all the things that overloaded his life and finally he realized he needed to take care of himself."
-- Noelene Clark
Photo: Richard Sambora was arrested on suspicion of drunk driving on March 25, 2008. Credit: Laguna Beach Police Department