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Garlic may do little to lower cancer risk

12:00 PM, January 10, 2009

Garlic1_2Garlic has a long history of use as a medicine. Studies in animals have shown garlic has chemical properties that may help with disease prevention, such as scavenging free radicals that can harm cells. And epidemiological research -- studies following the habits of large groups of people over time -- has shown that people who eat a diet rich in garlic have better health on numerous measures.

But a study published this week in the American Journal of Clinical Nutrition failed to find strong evidence for the benefits of garlic for reducing cancer risk. Researchers from the Korea Food and Drug Administration examined 19 studies in humans using criteria from the U.S. Food and Drug Administration's evidence-based review system for scientific evaluation of health claims. They found there was "no credible evidence" to support a relationship between garlic intake and reduced risk of gastric, breast, lung or endometrial cancer. There was "very limited evidence" to support a relationship between garlic intake and reduced risk of colon, prostate, esophageal, larynx, oral, ovary or renal cell cancers.

An editorial accompanying the study, however, says the analysis is too small to draw conclusions. Some of the 19 studies cited, for example, had a small number of subjects, wrote the author of the editorial, Richard S. Rivlin. Rivlin is a researcher with Weill Cornell Medical College in New York. He has received grant money for studies on garlic from Wakunaga of America, Ltd., which makes a garlic extract supplement. More research is needed, Rivlin said, to reconcile the new study's findings and previous scientific evidence that garlic is good for health.

-- Shari Roan

Photo credit: Joshua Roberts/For The Times

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Tami Dennis, who takes the word "skeptic" to previously uncharted territory, is the Times' Health and Science editor. She's adamant that pitches promoting awareness days, weeks or months are, by their nature, non-stories. And, because she's an adult, she refuses to use words like "veggies," "tummy" and "yummy."
Rosie Mestel, deputy Health and Science editor, studied genetics before abandoning flies, fungi and DNA for health/medical writing. Her hero is the biologist Ernst Haeckel, whose jellyfish paintings inspired snazzy chandeliers. Her favorite toast-spread is Marmite, a British delicacy made of yeast extract. Her least-favorite word is "millenniums."
Melissa Healy is a staff writer for the Health section reporting from Washington D.C. Healy's a veteran of The Times' National staff, having covered the Pentagon, Congress, poverty and social welfare, the environment, and the White House before shifting to Health in 2003. She writes frequently about mental health and human behavior, about federal health policy, prescription medication and ethics in medicine. More wonk than wellness freak, Healy chooses to believe in the health benefits of coffee and wine, and considers water a better work-out medium than beverage.
Karen Kaplan covers genetics, stem cells and cloning. She and colleague Thomas H. Maugh II comprise about 25% of the unofficial MIT-Alumni-in-Journalism Club, and she is proud to have taken more math (5) than English (0) courses in college. Her contributions to Booster Shots will, she hopes, appear more frequently than postings to her mommy blog.
Thomas H. Maugh II has been a science and medical writer at the Times for 23 years. Before that, he was on the staff of the journal Science for 13 years. He has bachelor's degrees in English and chemistry from MIT and a doctorate in chemistry from UC Santa Barbara.
After a brief stint as a sports writer, Shari Roan turned to health journalism and has covered the topic for The Times for 18 years. She is the author of three books and the mother of two daughters, both teenagers who refer to her as a "health freak." She likes to jog, watch baseball and is very happy that dark chocolate contains some health benefit.
Jeannine Stein writes about fitness, sports medicine and obesity for the Health section. She’s a gym rat from way back and never met an elliptical trainer she didn’t like. Well, maybe one or two. She tempers exercise with a steady diet of reality television because she believes it’s all about balance.