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Diabetes slows mental functions, even in middle-age

11:54 AM, January 5, 2009

Brain1Here's a good reason to get your blood sugar under control: Another study has linked diabetes with a decline in several types of mental functions. The study, published today in the journal Neuropsychology, also found that these mental deficits appear in people who are in the early stages of the disease and persist into old age.

Researchers at the University of Alberta in Edmonton, Canada, studied 41 adults with diabetes and 424 adults in good health. The study participants were between the ages of 53 and 90 and were tracked for several years. The findings support earlier studies that have found diabetes impairs cognition. But the new study also showed that the deficits seem to begin early in the course of the disease and are not limited to elderly people. The researchers also found that adults with diabetes scored worse on two of five mental processing tasks that were measured: executive functioning and speed. There were no differences between the two groups in memory, verbal fluency, reaction time and perceptual speed. The deficits detected were not enough to impair a person's ability to work or function in daily life, the authors said, but they appear to predict additional cognitive decline.

"Speed and executive functioning are thought to be among the major components of cognitive health," Roger Dixon, a co-author of the study, said in a news release. "There could be some ways to compensate for these declines, at least early and with proper management."

With diabetes reaching epidemic levels and affecting people of younger ages, Dixon suggested that health professionals should consider checking the cognitive status of people with more advanced cases of the disease. Last week, a study in the journal Annals of Neurology, showed that even modest increases in blood sugar levels in people who are not diabetic can lead to changes in the brain that impair mental function.

-- Shari Roan

Image: James Yang / For The Times

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Right now, there's no proven way to prevent the onset of Alzheimer's disease or Dementia. However, you may be able to reduce your risk of Alzheimer's disease by reducing your risk of heart disease. Many of the same factors that increase your risk of heart disease can also increase your risk of dementia. The main players appear to be blood pressure, cholesterol and blood glucose levels. Also, keeping active — physically, mentally and socially — also seems to reduce the risk of Alzheimer's disease. There are also numerous drugs being tested for the prevention and delay of Alzheimer’s and Dementia. The pharmaceutical research focus now is turning to prevention trials, and a number of studies are underway to test the effectiveness of various therapies in people without symptoms or who have only slight memory problems. Some of the drugs being tested are estrogen, Folate/B6/B12, Vitamin E, Aspirin, Naproxen, and Celebrex. Please refer to the Alzheimer’s Association http://www.alzinfo.org/alzheimers-research-prevention.asp or www.alz.org for more information and always consult your primary care physician.

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After a brief stint as a sports writer, Shari Roan turned to health journalism and has covered the topic for The Times for 18 years. She is the author of three books and the mother of two daughters, both teenagers who refer to her as a "health freak." She likes to jog, watch baseball and is very happy that dark chocolate contains some health benefit.
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