Booster Shots

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Obesity: you can't win for losing

12:09 PM, July 29, 2008

If you're overweight, you know the benefits of weight loss -- lowered risk of about a gazillion diseases, the big ones being heart disease, diabetes and some cancers. So you've changed your whole life, trading TV for exercise, fast food for less food and elevators for stairs.

Skeleton1 You've lost the weight! But before you start dancing and breaking out the Champagne -- make that sparkling water -- consider your bones.

While you've been re-sculpting your body, your bones have also been remodeling themselves, according to research at the University of Missouri, accepted for publication in a future issue of the Journal of the American College of Nutrition. Lo and behold, your bone density has decreased, and your bones are more fragile. The kicker is that this fragility persists even when you're in the maintenance phase of your new look.

Researchers examined protein markers of bone breakdown and formation in 37 obese, middle-aged adults who lost 20% of their weight through a severe calorie-restricted diet. They knew that moderate weight loss reduces bone mineral density, but they didn't know if bones return to normal density during post-diet weight maintenance.

Well, they don't. Author Pam Hinton, associate professor of nutritional sciences at the university, found that nine months after the weight loss, bones remained more fragile than before.

"Rapid rates of bone remodeling ... can increase bone fragility," says Pam Hinton, associate professor of nutritional sciences and author of the study. "People planning on losing a significant amount of weight should incorporate high-impact weight-bearing physical activity into their exercise routine and consume adequate calcium to improve bone health."

For a thorough "how-to" guide on weight loss, check out the June 9 Health section of the Los Angeles Times.

-- Susan Brink

Photo: Fredrik Nilsen. "Dancing Skeletons" by Liz Craft.

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Tami Dennis, who takes the word "skeptic" to previously uncharted territory, is the Times' Health and Science editor. She's adamant that pitches promoting awareness days, weeks or months are, by their nature, non-stories. And, because she's an adult, she refuses to use words like "veggies," "tummy" and "yummy."
Rosie Mestel, deputy Health and Science editor, studied genetics before abandoning flies, fungi and DNA for health/medical writing. Her hero is the biologist Ernst Haeckel, whose jellyfish paintings inspired snazzy chandeliers. Her favorite toast-spread is Marmite, a British delicacy made of yeast extract. Her least-favorite word is "millenniums."
Melissa Healy is a staff writer for the Health section reporting from Washington D.C. Healy's a veteran of The Times' National staff, having covered the Pentagon, Congress, poverty and social welfare, the environment, and the White House before shifting to Health in 2003. She writes frequently about mental health and human behavior, about federal health policy, prescription medication and ethics in medicine. More wonk than wellness freak, Healy chooses to believe in the health benefits of coffee and wine, and considers water a better work-out medium than beverage.
Karen Kaplan covers genetics, stem cells and cloning. She and colleague Thomas H. Maugh II comprise about 25% of the unofficial MIT-Alumni-in-Journalism Club, and she is proud to have taken more math (5) than English (0) courses in college. Her contributions to Booster Shots will, she hopes, appear more frequently than postings to her mommy blog.
Thomas H. Maugh II has been a science and medical writer at the Times for 23 years. Before that, he was on the staff of the journal Science for 13 years. He has bachelor's degrees in English and chemistry from MIT and a doctorate in chemistry from UC Santa Barbara.
After a brief stint as a sports writer, Shari Roan turned to health journalism and has covered the topic for The Times for 18 years. She is the author of three books and the mother of two daughters, both teenagers who refer to her as a "health freak." She likes to jog, watch baseball and is very happy that dark chocolate contains some health benefit.
Jeannine Stein writes about fitness, sports medicine and obesity for the Health section. She’s a gym rat from way back and never met an elliptical trainer she didn’t like. Well, maybe one or two. She tempers exercise with a steady diet of reality television because she believes it’s all about balance.